299 IN SITU ANALYSIS OF GLUCOSE IN COSMETIC FORMULATIONS
FUNDING
Authors state no funding involved.
AUTHORS’ CONTRIBUTIONS
Georgia Eleni Tsotsou: Conceptualization, Formal analysis, Investigation, Methodology,
Supervision, Validation, Writing, review &editing, Anastasia Kyriaki Tsara: Investigation,
Validation.
LIST OF ABBREVIATIONS
BEF DIL before any dilution
k thousand
[Glu] Glucose concentration
GOD Glucose Oxidase
mPa milliPascal
n number of replicates
NMF Natural Moisturizing Factor
O/W oil-in-water emulsion
POD Peroxidase
QC Quality Control
R2 correlation coefficient
rpm rounds per minute
WR Working Reagent
REFERENCES
(1) Lee SH, Bae IH, Lee ES, Kim HJ, Lee J, Lee CS. Glucose exerts an anti-melanogenic effect by
indirect inactivation of tyrosinase in melanocytes and a human skin equivalent. Int J Mol Sci.
2020 21(5):1736–1748. doi:10.3390/ijms21051736
(2) Fiume MM, Bergfeld WF, Belsito DV, et al. Safety assessment of monosaccharides, disaccharides, and
related ingredients as used in cosmetics. Int J Toxicol. 2019 38:5S–38S. doi:10.1177/1091581818814189
(3) Patra V, Gallais Sérézal I, Wolf P. Potential of Skin microbiome, Pro- and/or pre-biotics to Affect Local
cutaneous Responses to UV Exposure. Nutrients. 2020 12(6):1795–1808. doi:10.3390/nu12061795
(4) Bockmühl D, Jassoy C, Nieveler S, Scholtyssek R, Wadle A, Waldmann-Laue M. Prebiotic
cosmetics: an alternative to antibacterial products. Int J Cosmet Sci. 2007 29(1):63–64.
doi:10.1111/j.1467-2494.2007.00355_2.x
(5) Al-Ghazzewi FH, Tester RF. Effect of konjac glucomannan hydrolysates and probiotics on the
growth of the skin bacterium Propionibacterium acnes in vitro. Int J Cosmet Sci. 2010 32(2):139–142.
doi:10.1111/j.1468-2494.2009.00555.x
(6) Thurlow LR, Stephens AC, Hurley KE, Richardson AR. Lack of nutritional immunity in diabetic skin
infections promotes Staphylococcus aureus virulence. Sci Adv. 2020 6(46):eabc5569. doi:10.1126/sciadv.
abc5569
FUNDING
Authors state no funding involved.
AUTHORS’ CONTRIBUTIONS
Georgia Eleni Tsotsou: Conceptualization, Formal analysis, Investigation, Methodology,
Supervision, Validation, Writing, review &editing, Anastasia Kyriaki Tsara: Investigation,
Validation.
LIST OF ABBREVIATIONS
BEF DIL before any dilution
k thousand
[Glu] Glucose concentration
GOD Glucose Oxidase
mPa milliPascal
n number of replicates
NMF Natural Moisturizing Factor
O/W oil-in-water emulsion
POD Peroxidase
QC Quality Control
R2 correlation coefficient
rpm rounds per minute
WR Working Reagent
REFERENCES
(1) Lee SH, Bae IH, Lee ES, Kim HJ, Lee J, Lee CS. Glucose exerts an anti-melanogenic effect by
indirect inactivation of tyrosinase in melanocytes and a human skin equivalent. Int J Mol Sci.
2020 21(5):1736–1748. doi:10.3390/ijms21051736
(2) Fiume MM, Bergfeld WF, Belsito DV, et al. Safety assessment of monosaccharides, disaccharides, and
related ingredients as used in cosmetics. Int J Toxicol. 2019 38:5S–38S. doi:10.1177/1091581818814189
(3) Patra V, Gallais Sérézal I, Wolf P. Potential of Skin microbiome, Pro- and/or pre-biotics to Affect Local
cutaneous Responses to UV Exposure. Nutrients. 2020 12(6):1795–1808. doi:10.3390/nu12061795
(4) Bockmühl D, Jassoy C, Nieveler S, Scholtyssek R, Wadle A, Waldmann-Laue M. Prebiotic
cosmetics: an alternative to antibacterial products. Int J Cosmet Sci. 2007 29(1):63–64.
doi:10.1111/j.1467-2494.2007.00355_2.x
(5) Al-Ghazzewi FH, Tester RF. Effect of konjac glucomannan hydrolysates and probiotics on the
growth of the skin bacterium Propionibacterium acnes in vitro. Int J Cosmet Sci. 2010 32(2):139–142.
doi:10.1111/j.1468-2494.2009.00555.x
(6) Thurlow LR, Stephens AC, Hurley KE, Richardson AR. Lack of nutritional immunity in diabetic skin
infections promotes Staphylococcus aureus virulence. Sci Adv. 2020 6(46):eabc5569. doi:10.1126/sciadv.
abc5569








































































