324 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Table I Ingredients and Their Comedogenicity and Irritancy Ingredient Grade (0- 5) Comedo. ? Irrit. ½ Ingredient Grade (0- 5) Comedo.? Irrit.½ I. Lanolins and derivatives Acetylated lanolin 0 0 Acetylated lanolin alcohol 4 2 Anhydrous lanolin 0-1' 0 Lanolin alcohol 0-2* 0 Lanolin oil 0-1' 0 PEG 16 lanolin (Solulan 16) 4 3 PEG 75 lanolin 0 0 Laneth- 10 2 1 PPG 12 PEG 65 lanolin oil 2 0 II. Fatty acids and their derivatives Caprylic acid 1 3 Capric acid 2 2 Lauric acid 4 Myristic acid 3 0 Palmitic acid 2 0 Stearic acid 2 - 3' 0 Eicosanoic acid 2 0 Behenic acid 0 0 Ascorbyl palmitate 2 0 Behenyl erucate 0 0 Butyl stearate 3 0 Cetyl acetate 4 2 Cetyl ester NF 1 1 Cetyl palmitate 0 0 Decyl oleate 3 0 Di (2 ethylhexyl) succinate 2 0 Dioctyl malate 3 1 Dioctyl succinate 3 2 Diisopropyl adipate 0 0 Diisopropyl dimerate 0 0 Ethylhexyl palmitate 4 0 Ethylhexyl pelargonate 2 3 Isodecyl oleate 2- 3' 1 - 2 Isopropyl isostearate 5 0 Isopropyl linolate 4 2 Isopropyl myristate 5 3 Isopropyl palmitate 4 1 Isostearyl neopentanoate 3 3 Isostearyl isostearate 4 1 Myristyl lactate 4 2 Myristyl myristate 5 2 Octyldodecyl stearate 0 0 Octyldodecyl stearoyl stearate 0 0 Stearyl heptanoate 4 0 Tridectyl neopentanoate 0 3 III. Alcohols• sugars and their derivatives SD alcohol 40 0 0 Isopropyl alcohol 0 0 Myristyl alcohol 2 4 Cetyl alcohol 2 2 Isocetyl alcohol 4 4 Cetearyl alcohol 2 1 Oleyl alcohol 4 2 Stearyl alcohol 2 2 Cetearyl alcohol q- ceteareth 20 4 Ceteareth-20 2 3 Propylene glycol 0 0 Butylene glycol 1 0 Hexylene glycol 0-2* 0- PG caprylate/caprate 2 2 PG dicaprylate/caprate 1 0 PG dipelargonate 2 2 PG laurate 0 3 PG monostearate 0- 3 0- Ethylene glycol monostearate 0 0 Glucose glutamate 0 0 Sorbitol 0 0 Sorbitan laurate 1- 2' !- 2 Sorbitan sesquinoleate 0- !* 0 Sorbitan oleate 3 0 Sorbitan stearate 0 Sorbitan isostearate 1-2' 0 PEG 40 sorbitan laurate 0 0 Polysorbate 20 0 0 Polysorbate 80 0 0 Glycerin 0 0 Glycereth-26 0 0 Glyceryl-3-diisostearate 4 0 Glyceryl stearate NSE 1 0 Glyceryl stearate SE 3 2 Glyceryl tricapylo/caprate 1 1 Behenyl triglyceride 0 0 Pentaerythrital tetra isostearate 2 0 Pentaerythrital tetra capra/ caprylate 0 0 Wheat germ glyceride 3 2 Polyglyceryl- 3-diisostearate 4 0 Polyethylene glycol (PEG 400) ! 0 Sucrose distearate 0 2 Sucrose stearate 0 0 PEG 120 methyl glucose dioleate 0 0 PEG 8 stearate 3 PEG 20 stearate ! 0 PEG 100 stearate 0 0

COMEDOGENICITY 325 Table I (continued) Ingredient Grade (0-5) Comedo. •- Irrit. :• Ingredient Grade (0 - 5) Comedo.•- Irrit.:• PEG 100 distearate 2 0 PEG 150 distearate 2 0 PEG 200 dilaurate 3 2 Laureth-4 5 4 Laureth-23 3 0 Steareth-2 2 2 Steareth- 10 4 3 Steareth-20 2 1 Steareth- 100 0 0 Oleth-3 5 2 Oleth-5 3 2 Oleth- 10 2 1 Oleth-20 1 0 Oleth-3 phosphate 2 2 Triacetin 0 0 PPG 5 Ceteth 10 phosphate 4 2 PPG 2 myristyl propionate 3 2 PPG 10 cetyl ether 3 1 PPG 30 cetyl ester 0 0 PPG 50 cetyl ester 0 0 PEG 78 glyceryl monococoate 0 1 PEG 8 castor oil 1 1 PEG 40 castor oil 0 0 Polypentaerythrital tetralaurate 0 0 IV. Waxes Candelilla wax 1 0 Carnuba wax 1 0 Ceresin wax 0 0 Beeswax 0- 2 * 0 Lanolin wax 1 0 Jojoba oil 0-2* 0 Sulfated jojoba oil 3 2 Emulsifying wax NF 0 0- 2' V. Thickeners Carboxymethylcellulose 0 0 Carboxypropylcellulose 1 0 Hydroxypropylcellulose 1 0 Magnesium aluminum silicate 0 0 Carbomer 940 1 0 Bentonite 0 0 Kaolin 0 0 Talc 1 0 PVP 0 0 VI. Oils* Cocoa butter 4 0 Coconut butter 4 0 Hydrogenated vegetable oil 3 0 Sesame oil Corn oil Avocado oil Evening primrose oil Mink oil Soybean oil Shark liver oil Cotton seed oil Peanut oil Olive oil Sandalwood seed oil Almond oil Apricot kernel oil Hydrogenated polyisobutane Castor oil Hydrogenated castor oil Chaulmoogra oil Babassu oil Squalane Maleated soybean oil Safflower oil Sunflower oil Mineral oil VII. Pigments D & C red #3 D & C red #4 D & C red #6 D & C red #7 D & C red #9 D & C red # 17 D & C red # 19 D & C red #21 D & C red #27 D & C red #30 D & C red #33 D & C red #36 D & C red #40 Ultamarine violet Iron oxides Carmine Titanium dioxide VIII. Silicones Simethicone Dimethicone Cyclomethicone IX. SteroIs Cholesterol Soya sterol Peg 5 soya sterol 3(1)** 0 3 0 3(2) 0 3 2 3(2) 3 0 3 2 3 2 2 0 2(1) 0 2 0 2(I) 0 2(1) 0 1 2 1 0 1 0 1 0 1 0 1 0 0 0 0 0 0 0 0-2 0 0 0 0 (continued)