134 JOURNAL OF COSMETIC SCIENCE Table VI Distribution of Forehead Wrinkle Scores According to the Five-Grade Scale Wrinkle grade n (%) 1 54 (32.9) 2 24 (14.6) 3 35 (21.3) 4 34 (20.7) 5 17 (10.4) Total 164 Table VII Consistency of Agreement Regarding the Eye-Corner Wrinkles and Forehead Wrinkles of 164 Subjects, Scored by Five General Examiners Eye corners Forehead Examiner fo / NT* K fo / NT* K YT 86/164 0.407 79/164 0.328 TF 89/164 0.426 79/164 0.322 KT 114/164 0.604 93/164 0.441 AO 84/164 0.400 87 / 164 0.391 HO 122/164 0.657 79/164 0.332 * Number of scores in agreement with the consensus panel (fo) divided by total number (NT). 5, and the ages at which the wrinkle score obtained from this slope became 3 are shown in Figure 6. The slope was high, in the order of: eye corners forehead lower eyelids upper eyelids mouth angles nasolabial grooves cheeks glabella. The ages at which the score became 3 were the early 30s for the eye corners and lower eyelids, the late 40s for the upper eyelids, nasolabial grooves, and forehead, the late 40s for the glabella and the mouth angles, and the middle 50s for the cheeks. CLINICAL TEST OF WRINKLE-IMPROVING AGENT The demographic details of the subjects in the clinical test are shown in Table IX. Their mean age was 42.4 years, and scores 6 on the nine-grade scale were observed in 33%. The results of the clinical test are shown in Table X. The wrinkle scores at the eye corners were significantly improved after the use of the agent for eight weeks. DISCUSSION In a preliminary study, the results using the photo scales were compared with those using descriptive standards, and the usefulness of the photo scales was confirmed (data not shown). Griffiths et al. (8) evaluated photodamage according to photo scales and descriptive standards and found the kappa value significantly higher for the former (0.31) compared to the latter (0.11), suggesting the usefulness of photo scales. The results of our preliminary evaluation were consistent with their findings. Here, a five- grade photo scale was compared with a nine-grade scale, and the former scale was

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