STABILITY OF FERULIC ACID 487 (b-1): Stability of Serums 4-8 @ RT/light[8] Serum AspectColorOdor 4 blank No change pH 5.0 No change 6.0 Slight C change 5 blank No change pH 5.0 Impossible to formulate 6.2[7] No change 6 blank No change pH 5.0 Impossible to formulate 6.0 No change 7 [1] blank No change pH 5.0 Crystal↓ 6.0 No change 8 blank No change pH 5.0 Crystal↓ 6.0 Slight C change (c-1): Stability of Serums 4-8 @ 4°C/dark[8] Serum AspectColorOdor F.A%[3] (4°C/dark) 4 blank No change — pH 5.0 No change 0.989[5] 6.0 No change 0.990[5] 5 blank No change — pH 5.0 Impossible to formulate N/A 6.2[7] No change 0.990[4] 6 blank No change — pH 5.0 Impossible to formulate N/A 6.0 Diphase 0.990[4] 7 [1] blank No change — pH 5.0 Crystal↓ 0.991[5] 6.0 No change 0.991[5] 8 blank No change — pH 5.0 Crystal↓ N/A 6.0 No change 0.991[5]
JOURNAL OF COSMETIC SCIENCE 488 (d-1): Stability of Serums 4-8 @ 37°C/dark[8] Serum AspectColorOdor 4 blank No change pH 5.0 No change 6.0 C change 5 blank No change pH 5.0 Impossible to formulate 6.2[7] Severe C change 6 blank No change pH 5.0 Impossible to formulate 6.0 Diphase, severe C change 7 [1] blank No change pH 5.0 Severe C & O change 6.0 Severe C & O change 8 blank No change pH 5.0 Severe C & O change 6.0 Severe C change (e-1): Stability of Serums 4-8 @ 45°C/dark[8] Serum AspectColorOdor ⊿pH[2] F.A%[3] (RT/dark) 4 blank No change -0.4 — pH 5.0 Slight C & O change -0.3 0.713[5] 6.0 Severe C change +1.1 0.476[5] 5 blank No change -0.4 — pH 5.0 Impossible to formulate — N/A 6.2[7] Severe C change +1.4 0.531[4] 6 blank No change +0.0 — pH 5.0 Impossible to formulate — N/A 6.0 Diphase, severe C & O change +0.8 0.689[4] 7 [1] blank No change — — pH 5.0 Severe C & O change — 0.679[5] 6.0 Severe C & O change — 0.624[5] 8 blank No change 0 — pH 5.0 Severe C & O change — N/A 6.0 Severe C change +1.4 0.670[5] [1] In W/O and W/Si formulae, pH can’t be detected, so pH here refers only to that of water phase. [2] pH here refers to the pH difference between the initial one and the one incubated under RT/45°C after 2 months. [3] F.A% here refers to the remaining percentage of FA from initial 1%. For example, 0.720 represents that after 2 months’ storage. F.A decreased from 1.0% to 0.720% in formula. [4] Tested after 42 days’ storage. [5] Tested after 60 days’ storage. [6] Below this pH, 1% of F.A can not be totally dissolved in the water phase of cream 3. [7] Below this pH, 1% of F.A can not be totally dissolved in the water phase of serum 5. [8] F.A retention percentage @ RT/light and 37°C/dark was not detected.
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