TRICLOSAN ASSAY 41 A [] 4 I• 4 I• rain Figure 3. HPLC trace of a deodorant soap preparation purified (A) by SFE (0.103 g) or (B) by the method reported in the literature (6) (0. 120 g). Conditions and peak identification are as in Figure 2 2 = triclocarban. CONCLUSIONS In conclusion, the first SFE method has been developed for the rapid and selective isolation of triclosan from deodorant sticks and soaps. The proposed procedure provides a higher degree of sample purification than classical liquid extraction (6). Since SFE allows the automation of the entire extraction process, improved precision and faster method development are achieved, in comparison with conventional manual sample preparation. Moreover, the drastic reduction of hazardous solvents required represents another advantage of SFE. Because of minimal sample handling, ease of operation, good accuracy, and reproducibility, the SFE procedure is suitable for routine quality control analyses of triclosan in deodorants, particularly to verify the conformance of the com- mercial products to the current legislation. ACKNOWLEDGMENTS The authors thank Hewlett-Packard (Italy) for the loan of the HP 7680A instrument. Financial support from the Consiglio Nazionale delle Ricerche, Piano Finalizzato Chim-

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