478 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Basic yellow 57 absorption percutaneous, Tesafilm stripping method, humans, 47 Benzocaine absorption mouse skin, 327 Benzoic acid absorption skin, regional, male and female rats, in vitro, 127 preservatives resistance, P. cepacia, cosmetic formulations, 197 Bonds disulfide hair reduction kinetics, 301 Brij 35, see Laureth 23 n-Butanol, see Alcohols, butyl Butoxyethanol emulsions micro-, comparison, esters, stability effects, 73 2-Butoxyethanol, see Butoxyethanol C external blue 12, see Solvent blue 35 C external yellow 10, see Metanil yellow Caffeine absorption percutaneous, Tesafilm stripping method, humans, 47 Carcinogens nitrosamines cosmetics, denitrosation, chemiluminescence, analysis, 41 Caucasians hair analysis, 361 combing, effects, comparison, Negroes, 213 Central nervous system stimulants caffeine absorption, percutaneous, Tesafilm stripping method, humans, 47 Chemiluminescence nitrosamines following denitrosation, cosmetics, analysis, 41 Chinese hair analysis, 361 CI-12245, see Basic red 76 CI-12250, see Basic brown 16 CI-12251, see Basic brown 17 CI-12719, see Basic yellow 57 CI-13065, see Metanil yellow CI-61554, see Solvent blue 35 Clearance, see Excretion Coefficient of friction skin methodology, 463 Collagen skin aging, rat and human, 451 tissues aging, animals, 439 Concentration aluminum salts antiperspirants, 255 benzocaine absorption, mouse skin, 327 esters effects, stability, microemulsions, 73 preservatives cosmetics, formulations, lack, effects, P. cepacia, 197 reducing agents hair, kinetics, 301 surface active agents hydrocortisone microemulsions, 335 water skin, stratum corneum, diffusivity, equations, 191 Conditioners skin effects, pigs, 317 Contamination D&C Red No. 9 allergens, 273 microbiological cosmetics, and topical preparations, analysis, FDA methods, 35 cosmetics, formulations, P. cepacia, resistance, 197 red lake C amine aromatic amines, 273 Corticosteroids, see Steroids, cortico- Cortisone absorption skin, regional, male and female rats, in vitro, 127 Cosmetics contamination microbiological, analysis, FDA methods, 35 P. cepacia, resistance, preservatives, pH, 197 dyes absorption, percutaneous, Tesafilm stripping method, humans, 47 D&C Red No. 9, purification, 273 microemulsions skin, 335 nitrosamines denitrosation, chemiluminescence, analysis, 41 odors perfumes, complexity and psychophysical perception, humans, 83 skin effects, analysis, 451 emulsions, w/o, comparison, o/w, emollient effects, humans, 263 evaluations, methodology, 407 moisturization, impedance analysis, 419 toxicity rabbits, 215 Creams depilatories skin, irritation, effects, electric potential, guinea pigs, 159 perfumes odors, complexity and psychophysical perception, humans, 83 D&C Red No. 9 synthesis nonallergenic, 273 Decylamine adsorption keratin fibers, 285 Degradation, see Stability Deodorants soaps effects, methodology, 351 Depilatories toxicity skin, irritation, effects, electric potential, guinea pigs, 159 Diameter hair fibers, load-elongation, uncoiling, 227 1,12-Diaminododecane adsorption keratin fibers, 285 N-Diethanolnitrosamine, see N- Nitrosodiethanolamine Diffusion benzocaine mouse skin, 327 dyes cosmetics, percutaneous, Tesafilm stripping method, humans, 47 reducing agents hair, kinetics, 301 water skin, transepidermal loss, equations, 191 stratum corneum, electrometry, 383 Dipyrithione effects skin, cellular metabolism, antidandruff mechanism, in vitro, 1 Disinfectants triclocarban deodorant effects, methodology, 351 Disulfides hair content, beard and scalp 361 Dithiothreitol effects hair reduction kinetics, 301 n-Dodecylamine, see Lauramine Dressings Hill Top Chamber tests, patch, occlusivity, humans, 13 Drugs, adverse reactions see also Toxicity lanolin hydrogenated alkanediols, allergens, patients and animals, 99 Dyes cosmetics absorption, percutaneous, Tesafilm stripping method, humans, 47 D&C Red No. 9 synthesis, nonallergenic, 273 red lake C amine purification, 273 Sudan I allergens, guinea pigs, 273

SUBJECT INDEX 479 Elasticity hair load-elongation, uncoiling, 227 skin aging effects, 451 Elastin skin aging, rat and human, 451 Electric potential skin effects, irritation, evaluations, guinea pigs, 159 Electrolytes effects alkylamine sorption, keratin fibers, 285 Electrometry skin capacitance, 383 moisturization, impedance, 419 Elimination, see Excretion Emollients skin effects, 241 urea absorption, regional, male and female rat skin, in vitro, 127 Emulsions micro- esters, stability, effects, structure, stabilizers, 73 hydrocortisone stability, 335 oil-in-water comparison, water-in-oil, emollient effects, human skin, 263 water-in-oil comparison, oil-in-water, emollient effects, human skin, 263 hydrocortisone stability, 335 Enthalpy alkylamines sorption, keratin fibers, 285 Entropy alkylamines sorption, keratin fibers, 285 Equations diffusion water, stratum corneum, transepidermal loss, 191 friction skin, methodology, 463 hair setting, relaxation, factors, 205 Equipment electrodynamometer skin viscoelasticity measurements, 241 Thran spray gun bacterial sampling, 351 Essential oils, see Oils, essential Esters emulsions micro-, stability, effects, structure, stabilizers, 73 Ethyl acetate emulsions micro-, stability, effects, structure and stabilizers, 73 Excretion polyoxyethylene lauryl ethers mice, 263 Fatty acid esters toxicity comedogenicity, rabbits, 215 Formaldehyde preservatives resistance, P. cepacia, cosmetic formulations, 197 Formic acid effects epidermis, swelling, comparison, hair, wool, in vitro, 21 Formulations benzocaine absorption, mouse skin, 327 microemulsions hydrocortisone stability, 335 Fragrances, see Perfumes Friction skin evaluation, methodology, 463 Fungicides Oenzoic acid absorption, regional, male and female rat skin, in vitro, 127 Glycerin lotions skin, moisture, 383 Glyceryl oleate combination, propylene glycol hydrocortisone stability, 335 Glycosaminoglycans skin aging, rat and human, 439 Hair analysis racial differences, 361 combing dry, and wet, Negroes and Caucasians, 213 hydration swelling, comparison, epidermis, wool, in vitro, 21 reduction kinetics, 301 setting relaxation, factors, equations, 205 uncoiling load-elongation, 227 Hair sprays effects setting, relaxation, equations, 205 Heat, see Temperature n-Heptanol, see Alcohols, heptyl Hexadecane microemulsions hydrocortisone stability, 335 n-Hexadecane, see Hexadecane Hexane microemulsions hydrocortisone stability, 335 n-Hexanol, see Alcohols, hexyl Humidity, see Moisture Hydration keratin swelling, epidermis, comparison, hair, wool, in vitro, 21 skin evaluation, methodology, 419 Hydrocarbons oils hydrocortisone microemulsions, 335 Hydrocortisone microemulsions stability, 335 Hydrogen ion concentration cosmetics resistance, P. cepacia, formulations, 197 effects alkylamine sorption, keratin fibers, 285 hair reduction kinetics, 301 Hydrophilic-lipophilic balance emulsions effects, emollient, w/o, comparison, o/w, human skin, 263 microemulsions hydrocortisone, 335 Hypersensitivity, see Allergies Impedance skin moisturization, analysis, 419 Ions inorganic collagen tissues, aging, animals, 439 Irritants skin effects, electric potential, guinea pigs, 159 Isomers alkanediols lanolin hydrogenated, identification, synthesis, effects, patients and animals, 99 Isopropanol, see Alcohols, isopropyl Keratin fibers adsorption, alkyl amines, 285 hydration swelling, epidermis, comparison, hair, wool, in vitro• 21 Keratolytic agents tretinoin irritation, skin, effects, electric potential, guinea pigs, 159 Keratosis cosmetics rabbit test, 215 Kinetics reduction hair, 301 Lanolin toxicity lack, comedogenicity, rabbits, 215 Lanolin derivatives toxicity comedogenicity, rabbits, 215 Lanolin hydrogenated allergens isolation, identification, synthesis, effects, patients and animals, 99 Lauramine adsorption keratin fibers, 285