260 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS Figure 5. Stratum corneum of the human skin transplant. 5B. After l0 strippings. from their 10% w/w aqueous solutions and of Aqualizer incorporated into four different cosmetic bases in the same ratio. The results presented indicate that the highest stratum corneum uptake was from the aqueous solution of Aqualizer. The NMF condensate, which is a protein sugar complex, was retained by the stratum corneum at lower con- centrations. Therefore, the higher stratum corneum uptake of Aqualizer may be attrib- uted to the presence of urea and lactic acid which are known to act as diffusion pro-

HUMAN SKIN GRAFTED NUDE MOUSE 261 Figure 5. Stratum corneum of the human skin transplant. 5C. After 20 strippings. moters for many other substances (21). In fact, those additives themselves had high affinities for the stratum corneum when they were applied as single substances as is shown in Table II. All the cosmetic bases employed for the present investigation seem to have reduced the amount of Aqualizer retained by the stratum corneum (Table III). However, the lotion-

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