ANTIPRURITIC EVALUATION 65 REFERENCES (1) D. Sinclair, Mechanisms of Cutaneous Sensation (Oxford University Press, New York, 1981), pp. 256- 259. (2) L. Chapman, H. Goodell, and G. Wolff, "Structures and Processes Involved in the Sensation of Itch," in Advances in Biology of Skin, Cutaneous Innovation, W. Montagna, Ed. (Pergamon Press, New York, 1960), Vol. 1, pp. 161-186. (3) S. Rothman, "Pathophysiology of Itch Sensation," in Advances in Biology of Skin, Cutaneous Innovation. W. Montagna, Ed. (Pergamon Press, New York, 1960), Vol. 1, pp. 189-201. (4) D. Sinclair, "Psychophysiology of Cutaneous Sensation," in The Physiology and Pathophysiology of the Skin, A. Jarrett, Ed. (Academic Press, New York, 1973), Vol. 2, pp. 440-441. (5) E. B. Titchener, A Text Book of Psychology, Part I (Macmillan, New York, 1909). (6) H. E. Torebj6rk, Afferent C-units responding to mechanical, thermal and chemical stimuli in human non-glabrous skin, Acta Physiologica Scandinavica, 153, 374-390 (1974). (7) H. E. Torebj6rk, (1979) "Discussion Section," in Sensory Functions of the Skin of Humans, D. Kenshalo, Ed. (Plenum Press, New York, 1979), pp. 411-412. (8) W. Magerl, R. A. Westerman, B. Moehner, and H. O. Handwerker, Properties of transdermal histamine iontophoresis: Differential effects of season, gender, and body region, J. Invest, Dermatol., 94, 347-352 (1990). (9) P. Bierring, and L. Arendt-Nielsens, A quantitative comparison of the effects of local analgesics on argon laser induced cutaneous pain and on histamine induced wheal, flare and itch, Acta Derre. Venereol., 70, 126-131 (1990). (10) S. Weinstein, "Intensive and Extensive Aspects of Tactile Sensitivity as a Function of Body Part, Sex and Laterality", in The Skin Senses, D. Kenshalo, Ed. (C. C. Thomas, Springfield, Ill, 1968), pp. 195-218. (11) S. Weinstein, Effects of local anesthetics on tactile sensitivity thresholds for cutaneous and mucous membranes, J. Invest. Dermatol., 69, 136-145 (1977). (12) C. Weinstein, R. Drozdenko, and S. Weinstein, Evidence supporting a new model for the evaluation of skin irritation, J. Soc. Cosmet. Chem., 39, 315-320 (1988).