a , Shampoo Extract (Scan 1928) 100.0- 263 50.0 43 115 77 91 171 278 ..,,..., .,I,.,,,..,I.I.,, .... ,,.., I. i I * I ß I - I ' i ß i * i ß i ,-i i M/Z 50 1 O0 150 200 250 b, 100.0- 50.0- Moskene Standard 43 263 , i , i , i ,I , I , I, I ' I ' ! ' I ' I ' I '1 ' I ' I ' I ' I ' I-' I ' I ' I ' I ' • ' I ' I , I M/Z 50 1 O0 150 200 250 Figure 6. (a) Electron impact mass spectrum of scan 1928 for the shampoo extract shown in Figure 4. (b) Electron impact mass spectrum of a moskene standard solution.

276 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS a. 6.4 211 Shampoo Extract 100.0 228 15.5 278 6.2 297 RIO 1200 1300 1400 1500 1600 1700 1800 1900 2000 SCAN 11:00 11:55 12:50 13:45 14:40 15:35 16:30 17:25 18:20 TIME b. 5.6 211 100.0 228 Shampoo Extract Spiked With NMDDA 14.9 278 6.4 297 RIO [ I [ • I ' [ • I ' I ' [ I [ ] I I [ I /[ [ I I , I ' I 1200 1300 1400 1500 1600 1700 1800 1900 2000 SCAN 11:00 11:55 12:50 13:45 14:40 15:35 16:30 17:25 18:20 TIME Figure 7. (a) Mass chromatograms for a 0.2 p•l on-column injection of a shampoo extract at masses 211 (NMDDA), 228 (myristic acid), 278 (moskene), and 297 (musk xylol). The reconstructed ion chromato- gram is also shown. (b) Mass chromatograms and reconstructed ion chromatograms as described above for a 0.2 p•l on-column injection of a shampoo extract spiked with 0.3 p•l of a standard 88 ng/p•l NMDDA solution. Note the appearance of a new peak at scan 1510 for mass 211 in the spiked sample which is now well separated from the nitromusks and the myristic acid. This separation was carried out on a 30m DX-4 polar capillary column.