327 Microsponge Loaded Topical Gel drug delivery technology is expected to become a valuable drug delivery matrix substance for various therapeutic applications in the future. REFERENCES (1) D. R. Bickers, H. W. Lim and D. Margolis, The burden of skin diseases: 2004 a joint project of the American academy of dermatology association and the Society for investigative dermatology, J. Am. Acad. Dermatol. 55, 490–500 (2006). (2) A. Bhatia, J. F. Maisonneuve and D. H. Persing, “Propioni bacterium acnes and chronic diseases,” in: The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects: Workshop Summary, S. L. Knobler, S. O’Connor, S. M. Lemon, M. Najafi. Eds. (National Academies Press, Washington, DC, 2004), pp 74–80. (3) N Sibinovska, V. Komoni and K. Ancevska-Netkovska, Novel approaches in treatment of Acne vulgaris: Patents related to micro/nanoparticulated carrier systems, Maced. Pharm. Bull. 62(2), 11–24 (2016). (4) N. Jadhav, V. Patel and S. Mungekar, Microsponge delivery system: An updated review, current status and future prospects, J. Sci. Innov. Res. 2, 1097–1110 (2013). (5) S. Deshwal and A. K. Saxena, Microsponge delivery system: An overview, International Journal of Bio- pharmaceutics 5(1), 39–46 (2014). (6) J. Bikowski and J. Q. Del Rosso, Case reports: Benzoyl peroxide microsphere cream as monotherapy and combination treatment of acne, J. Drugs. Dermatol. JDD 7(6), 590–595 (2008). (7) A. Roy, Microsponge as a novel drug carrier system: A review, World Journal of Pharmaceutical Research 4(12), 680–701 (2015). (8) M. Dutil, Benzoyl peroxide: Enhancing antibiotic efficacy in acne management, Skin Therapy Let. 15(10), 5–7 (2010). (9) U.S. Food and Drug Administration, Classification of Benzoyl Peroxide as Safe and Effective and Revision of Labeling to Drug Facts Format, 2010. Topical Acne Drug Products for Over-The- Counter Human Use Final Rule, accessed December 2022, https://www.federalregister.gov/documents/2010/03/04/2010-4424/ classification-of-benzoyl-peroxide-as-safe-and-effective-and-revision-of-labeling-to-drug-facts. (10) M. E. Acevedo, C. Bregni and V. Mourino, Solubility and stability studies of benzoyl peroxide in non- polar, non-comedogenic solvents for use in topical pharmaceutical formulation developments, Lat. Am. J. Pharm. 30(9), 1737–1743 (2011). (11) T. Edwards, L. Cardwell, N. Patel and S. R. Feldman, Benzoyl peroxide gel stains synthetic fabrics less than cotton. J. Am. Acad. Dermatol. 85, 481–482 (2018). (12) R. Wester, R. Patel, S. Natch, J. Leyden, J. Melendres and H. Maibach, Controlled release of benzoyl peroxide from a porous microsphere polymeric system can reduce topical irritancy, J. Am. Acad. Dermatol. 24, 720–726 (1991). (13) M. Simonoska-Crcarevska, A. Dimitrovska and N. Sibinovska, Implementation of quality by design principles in the development of microsponges as drug delivery carriers: Identification and optimization of critical factors using multivariate statistical analyses and design of experiments studies, Int. J. Pharm. 489, 58–72 (2015). (14) R. Ravi and S. K. Senthil, Standardization of process parameters involved erythromycin microsponges by quasi emulsion solvent diffusion method, Int. J. Pharm. Dev. Technol. 3, 28–34 (2013). (15) S. Nacht and M. Katz, “The microsponge: A novel topical programmable delivery system,” in: Topical Drug Delivery Formulations, A. Amann. Ed. (Dekker, New York, 1990), 42, pp. 229–325. (16) J. N. Bollinger, D. Lewis, and V. M. Mendez, Benzoyl peroxide stability in pharmaceutical gel preparations, J. Pharm. Sci. 66(5), 718–722 (1977). (17) M. Jelvehgari, M. R. Siahi-Shadbad, S. Azarmi, G. P. Martin and A. Nokhodchi, The microsponge delivery system of benzoyl peroxide: preparation, characterization and release studies, Int. J. Pharm. 308, 124–132 (2006).
328 JOURNAL OF COSMETIC SCIENCE (18) N. Akhtar, A. Verma and K. Pathak, Feasibility of binary composition in development of nanoethosomal glycolic vesicles of triamcinolone acetonide using Box-Behnken design: In vitro and ex vivo characterization, Artif. Cells Nanomed Biotechnol. 45, 1–9 (2016). (19) I. John, J. I. D’Souza, K. Jagdish, S. Saboji, G. Killedar and N. Harinath, Design and evaluation of benzoyl peroxide microsponges to enhance therapeutic efficacy in acne treatment. Accepted for presentation in 20th FAPA Congress, Bangkok, Thailand 2004: 28. (20)V .Jain and R. Singh, Dicyclomine-loaded eudragit-based microsponge with potential for colonic delivery preparation and characterization, Tropical Journal of Pharmaceutical Research 9(1), 67–72 (2010). (21) M. Orlu, E. Cevher and A. Araman, Design and evaluation of colon-specific drug delivery system containing Flurbiprofen microsponges, International Journal of Pharmaceutics 318, 103–117 (2006). (22) C. Yerram, F. Shaik, B. Rubia Y., V. Amaravathi, B. Mahitha and U. Aruna, Microsponges: A novel drug delivery system for controlled delivery of topical drugs, Int. J. Pharm. Res. Anal. 2(2), 79–86 (2012). (23)V .B. Patel, A. N. Misra and Y. S. Marfatia, Preparation and comparative clinical evaluation of liposomal gel of benzoyl peroxide for acne, Drug Dev. Ind. Pharm. 27(8), 863–870 (2001b). (24) Y. Zhang, M. Huo, J. Zhou, A. Zou, W. Li, C. Yao and S. Xie, DDSolver: An add-in program for modeling and comparison of drug dissolution profiles, AAPS J 12(3), 263–271 (2010). (25) H. Ali, I. N. Muhammad and N. Aslam, Formulation design and optimization of aceclofenac tablets (100 mg) using central composite design with response surface methodology. Lat. Am. J. Pharm. 33(6), 1009–1018 (2014). (26) H. Song, X. Cao, J. Ruan, X. Peng, J. Wang, C. Wang and C. Bao, Application of rotatable central composite design in the preparation and optimization of poly (lactic-co-glycolic acid) nanoparticles for controlled delivery of HSA, Nano Biomedicine &Engineering 3, 34–41 (2011). (27) E. Markova, M. Kostovska and T. K. Olumcheva, Development of microsponges as drug delivery carriers: Optimization of formulation variables using sequential experimental strategy, Mac. Pharm. Bull. 62(Suppl.), 663–664 (2016). (28) L. E. Eichenfield, J. L. Jorizzo, T. Dirschka, A. F. Taub, C. Lynde, M. Graeber and N. Kerrouche, Treatment of 2,453 acne vulgaris patients aged 12-17 years with the fixed-dose adapalene-benzoyl peroxide combination topical gel: Efficacy and safety, J. Drugs Dermatol. 9:1395–1401 (2010). (29) F. Nielloud, J. P. Mestres and G. Marti-Mestres, Consideration on the formulation of benzoyl peroxide at ambient temperature choice of non-polar solvent and preparation of submicron emulsion gels, Drug Dev. Ind. Pharm. 28(7), 861–870 (2002). (30) U. Shinde, S. Pokharkar and S. Modani, Design and evaluation of microemulsion gel system of nadifloxacin, Indian J. Pharm. Sci. 74(3), 237–247 (2012). (31) P. M. Sarat, M. Ajay, B. B. Nagendra, P. Prathyusha, N. Audinarayana and R. K. Bhaskar, Microsponge drug delivery system: A review, Journal of Pharmaceutical Research 4(5), 1381–1384 (2011). (32) J. I. D’souza, In-vitro antibacterial and skin irritation studies of microsponges of benzoyl peroxide, Indian Drugs 38(7): 23 (2001). (33) G. Derringer and R. Suich, Simultaneous optimization of several response variables, J. Qual. Technol. 12, 214–219 (1980). (34) P. Arya and K. Pathak, Assessing the viability of microsponges as gastro retentive drug delivery system of curcumin: Optimization and pharmacokinetics, Int. J. Pharm. 460, 1–12 (2014). (35) M. A. Badawi and L. K. El-Khordagui, A quality by design approach to optimization of emulsions for electrospinning using factorial and D-optimal designs, Eur. J. Pharm. Sci. 58, 44–54 (2014).
Purchased for the exclusive use of nofirst nolast (unknown) From: SCC Media Library & Resource Center (library.scconline.org)
































































































