CLEANSING BAR EVALUATION 319 Table V Skin Fluorescence After 24 Hours of Treatment With Soap Solutions in Finn Chambers. Values are Treated Minus Untreated Skin Readings Taken 24 Hours After Finn Chamber Removal (Ex 290 rim, Em 350 rim) Products Solution D A B C 8% 2% N 19 19 19 19 • 0.572 0.716 0.572 0.422 Sx 0.428 0.403 0.341 0.427 N 19 19 19 19 • 0.482 0.594 0.519 0.360 Sx 0.486 0. 308 0.407 0.454 The rate of water loss measured on lower forearms was increased after use of A in comparison to soap D (Table VIII). The amounts of fluorescent dye adsorbed about 12 hours after use of the products are slightly increased (versus untreated skin) due to use of classical soaps and significantly enlarged after use of A (Table IX). Table VI Evaluation of Cleansing With Soap Bars. Fluorescence of Skin Soiled With Anthracene Was Determined Before and After Cleansing Treatment Contamination Index* D A B C N 20 20 20 20 • 0.021 0.030 0.024 0.027 Sx 0.014 0.021 0.019 0.011 Fluorescence after cleansing - fluorescence before soiling Fluorescence of soiled skin - fluorescence before soiling Statistical Evaluation of Data (Paired t-test) Comparison t Value D/A 2.681 D/B 0.792 D/C 1.478 Thresholds of signijS'cance: DF = 19 t Value 95% 2.093 99% 2.861

D i 6.5 5.5 4.5 number of strips removed Fiõure 5. pH values ooe the soap-washed skin suroeace aoeter stripping. Table VII Changes in Cheek Skin Roughness (Rz values) After Five Days Use of Various Soaps (normalized values) Treated Treated Treated Treated R z Values Control* With D Control* With A Control* With B Control* With C Beginning of n 139 153 117 113 133 144 129 136 Test Period • 99.57 99.57 99.57 99.57 99.57 99.57 99.57 99.57 (Mondays) s 28.48 29.96 21.29 23.28 26.04 26.93 24.26 27.06 (= Oh) End of n 125 125 113 117 148 113 129 117 Test Period • 99.57 95.44 99.57 93.65 99.57 105.37 99.57 96.07 (Fridays) s 25.34 30.07 22.86 26.57 26.13 27.08 28.06 26.63 (= lh) * (Untreated) control = skin site, contralateral to treated (= 1 h) or to be treated (= 0 h) skin site. n = Number of measurements. Comparison o• the Products/Code lh A B C D DF 240 236 240 ?: 0.489 2.666 0.172 A DF 228 232 e 3.313 0.696 B DF 228 • 2.626