TESTING DEODORANTS WITH CHLOROPHYLL AND DERIVATIVES 75 Although numerous attempts have been made to develop a method for direct, quantitative appraisals of odors on skin, all of these endeav- ors proved to be unproductive. During these explorations, the me- tallic osmoscope (40) and several modifications of this instrument were discarded as useless for direct meas- urements of cutaneous odors. In fact, it was less reliable than the unaided nose. It is the author's firm conviction that the procedure for determinations of perspiratory odors which has been utilized in the in-vivo experiments presented in the last five charts of this report repre- sents the most reliable method available today and, also, that well- controlled trials of this method will yield information of practical value in studies of deodorants intended for applications to skins of human sub- jects. REFERENCES (1) Kuno, Y., "The Physiology of Human Perspiration," Churchill, I,td., London (1934). (2) Myers, V. C., "Endocrinology and Metabolism," D. Appleton and Co., New York, Vol. 3, pp. 512-513 (1922). (3) Best, C. H., and Taylor, N. B., "Physio- logical Basis of Medical Practice," Wil- liams and Wilkins Co., Baltimore, pp. 723-724 (1950). (4) Shaw, L. A., and Messer, A. C., Am. 5 t. Physiol., 95, 16 (1930). (5) KillJan, J. A., and Panzarella, F. P., "Proceedings of the Scientific Section of the Toilet Goods Association," No. 7, p. 3 (1947). (6) Hier, S. W., Cornbleet, T., and Bergeim, O., 7- Bid. Chem., 166, 327 (1946) also references 2, 8, 9, and I I. (7) Price, P. B., 7. Infect. Dis., 63, 301 (1938). (8) Plaggemeyer, H. W., and Marshall, E. K., Jr., Arch. Int. Med., 13, 159 (1913- 14). (9) Riggs, R. W., •t. Med. Res. (Boston), 24, 289 (1911). (10) Benedict, F. G., 7. Biol. Chem., 1, 263 (1904-05). (11) Talbert, G. A., Saiki, A. K., Carpenter, R. C., Bergmeyer, J., Staff, H., Borman, C., and Freeman, D., Ibid., 97, 426 (1931). (12) Porter, J. R., "Bacterial Chemistry and Physiology," John Wiley & Sons, lnc., New York, pp. 103-104 (1947). (13) Carpenter, T. N., Fox, E. L., and Se- reque, A. F., 7. Biol. Chem., 83, 211 (1929). (14) Kolmer, J. A., and Boerner, F., "Ap- proved Laboratory Technic," D. Ap- pleton-Century Co., New York (1941). (a) For aerobic cultures, see "Pour Plates," pp. 366-367 (b) for anaerobic cultures, see "Spray Plate Method," p. 369. (15) Pillsbury, D. M., Livingood, C. S., and Nichols, A. C., Arch. Dermatol. and Syphilol., 45, 61 (1942). (16) "Official and Tentative Methods of Analysis," A. O. A. C., 6th edition, pp. 140-141 (1945). (17) Review by Steele, C. C.,in O•ganic Chem- istry by Gilman, H., et aL, John Wiley & Sons, Inc., New York, Vol. lI, pp. 1294-1295 (1943). (18) Cook, E. F., and Martin, E. W., Rem- ington's Practice of Pharmacy, Mack Publishing Co., Easton, Pa., p. 441 (1948). (19) Haggard, H. W., 7. BioL Chem., 55, 131 (1923). (20) Haggard, H. W., and Greenberg, A., 5 t. Am. Meal. Assoc., 104, 2160 (1945). (21) Circular 198, U. S. Department of Agriculture, Washington, D.C., Dec. (1941). (22) Gump, W., "Soap and Sanitary Chemi- cals," and the GivaudanJan Issues of March and April (1945). (23) Killian, J. A., "The Proceedings of the Scientific Section of the Toilet Goods Association," No. 13, May (1950). (24) Traub, E. F., Newhall, C. A., and Fuller, J. R., Surg. Gynec. and Obst., 79, 205 (1944). (25) Udinsky, H. J., 5 t. Med. Soc. N. 7., 42, 15 (1945). (26) Pillsbury, D. M., and Nichols, A. C., 7. Invest. DermatoL, 7, 365 (1946). (27) Hawk, P. B., Oser, B. L., and Summer- son, W. H., "Practical Physiological Chemistry," The Blakiston Co., Phila- delphia, p. 716 (1949). (28) Fair, G. M., 7. New Engl. Water Works Assoc., 47, 248 (1933). (29) Killian, J. A., manuscript in prepara- tion for publication. (30) Klarmann, E.G., and Shternov, V. D., Soap and Sanitary Chemicals, issue of January (1941).

76 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS (31) See References 5 and 28. (32) KillJan, J. A., manuscript in preparation for publication. (33) Lovell, D. L., Surg. Gynec. and Obst., 80, 174 (1945). (34) Klarmann, E.G., Am. Perf. Ess. Oil Review, July (1948). (35) Coilings, G. H., Jr., Am. 5 r. Surg., 70, 58 (1945). (36) Bowers, W. F., Ibid., 73, 37 (1947). (37) Moss, N.H., Morrow, B. A., Long, R. C., and Raydin, I. S., ?. Am. Med. As- soc., 140, 1336 (1949). (38) Westcott, F. H., N.Y. State 5 t. Med., 50, 698 (1950). (39) Montgomery, R. M., and Nachtigall, H. B., Postgraduate Medicine, 8, 401 (195o). (40) Fair, G. M., and Wells, W. F., IVater tt/orks Eng., 87, 1051 (1934). THE BRITISH SOCIETY O DR. R. MATALON gave an in- teresting lecture at the January meeting on "Foams" wherein he dealt with factors influencing their stability, measuring stability by means of a wire frame suspended vertically in such a manner that it can be raised at a controlled speed. On February 1st, a very successful dinner was held, at which the guests of the Society were Mr. W. A. Poucher and Mr. C. A. Williams, the latter being the secretary of the Toilet Preparations and Perfumery Manufacturers' Federation. Rep- resentatives of the leading per- fumery houses were also present as guests of members. Dr. E. J. Moynahan, M.R.C.P., Consulting Dermatologist to Guy's Hospital, to Farnborough Hospital, to Orpington Hospital, to Sevenoaks Hospital, and who served in the F COSMETIC CHEMISTS R.A.F. as dermatological specialist during the recent war, gave a lec- ture on March 7th entitled "Cos- metics and Dermatitis." The Soci- ety invited members of the Toilet Preparations Federation to this lec- ture. Mr. H. Holmes, Secretary of the Society, recently incapacitated by a heart attack, is now on the mend. Returned from the hospital, Mr. Holmes is slowly catching up with correspondence. Everyone sincerely wishes him Godspeed in his re- covery. Editor's Note: We are intrigued b? the charges for the Society's An- nual Dinner in London, 10/6 (about $1.50) for members and 21/-(about $2.95) for non-members. To us in the "States," these prices are a re- minder of the distant past.