TRANEXAMIC ACID LIPOSOMES 381
382 JOURNAL OF COSMETIC SCIENCE 120 lOO o• 80 ._• c. •o .•_ ,_• • 40 • 20 o 7:2:1 (5%TA,+) 7:2:1 (10%TA,+) 7:2:1 (5%TA,-) 7:2:1 (10%TA,-) i i i i 0 30 60 90 120 Time (Days) a) at 4+ 1 øC 12] 721 (5%TA.+) 721 (10%TA.+) 721(5%TA-) •m•••• 1(10%TA") b) at 30+1 øC o 3] fid fid 120 Trne(Dsys) 120 [ • 7:2:1 (5% TA,+) 7:2:1 (10%TA,+) 100 7:2:1 (5%TA,-) 7:2:1 (10%TA,-) 80 60 40 20 0 • , C) at 45+1 øC o 30 60 90 120 Time (Days) Figure 1. Comparison of the percentages of TA remaining in liposomes when kept at (a) 4 +_ 1 ø (b), 30 + 1% (c) 45 + IøC for 0, 14, 30, 60, and 90 days. Symbols are the mean values of six determinations.
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