350 JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS T^sLF• 4--Evv•cT or Ac•Nc oN Acre NursER •N PRES•NC• OV W^T• ^• 45øC. Acid No. Acid No. Change in Soluble Acids at Start at 30 Days Acid No. (U.S.P. Method) Acetylated lanolin 0.96 1.01 4-0.05 Neutral to litmus Acetylated lanolin alcohols 0.19 0.24 4-0.05 Neutral to litmus Lanolin U.S.P. 0.77 0.82 4-0.05 Neutral to litmus Table 4 gives data on the change in acid number. It will be noted that after thirty days at 45øC., in the presence of water, all three test samples exhibited the same insignificant change in acid number. The results of this accelerated test agree with aging tests carried out at room tempera- ture for one year on anhydrous shelf samples. These extended tests are still being followed. Obviously, under conditions of normal use, the acety- lated products do not hydrolyze. Formulations prepared with the acety- lated lanolin alcohol product and sodium lauryl sulfate are stabilized by the inclusion of soap. COSMETIC FORMULATIONS The unusual properties of the acetylated lanolin derivatives prompted us to develop formulations which would demonstrate these properties in typical cosmetic preparations. Lotion Oil-in-Water This lotion formulation has a medium consistency, and is a smooth, emol- lient preparation of attractive appearance. It can be adapted by minor changes for use as either a hair groom, cleansing lotion or hand and body lotion. It has excellent stability and lends itself to simple manufacturing procedures. Formula No. 1 Acetylated lanolin alcohols (liquid fraction) ..................................... 8.0% Stearic acid ................................................................. 2.0 Glyceryl monostearate, neutral ................................................. 5 Amerchol L-101 ............................................................. 8.0 Mineral oil, 70 vis ........................................................... 17.0 Microcrystalline wax, 170 m. p ................................................. 4.0 Glycerin .................................................................... 4.0 Water ...................................................................... 56.1 Triethanolamine .............................................................. 4 Preservative and Perfume ..................................................... q. s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases of 85øC. Mix slowly until cool and remix the following day. VANISHING CREAM This is an emollient, vanishing cream type of preparation which could also serve as the basis for a brushless shave cream. It has smooth texture and excellent stability and can be readily adapted to a hand cream.

ACETYLATED LANOLIN DERIVATIVES 351 Formula No. 2 Acetylated Lanolin Alcohol (liquid fraction) ..................................... 3.0% Stearic acid ................................................................. 18.0 Cetyl alcohol ................................................................. 5 Amerchol L-101 .............................................................. 5 Sodium hydroxide ............................................................ 8 Propylene glycol .......................................................... 14.0 Water ...................................................................... 63.2 Preservative and Perfume ...................................................... q s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases at 85øC. Mix slowly until cool and remix the following day. ANTIPERSPIRANT CREAM Antiperspirants formulated with acetylated lanolin products impart a non-greasy, highly emollient film which does not interfere with the activity of the aluminum chlorhydroxide complex. This formulation has a glossy surface and a smooth texture and is quite resistant to drying out. Formula No. 3 Acetylated lanolin... or ... Acetylated lanolin alcohols (liquid iYaction) ..................................... :2.0% Spermaceti .................................................................. 4.0 Propylene glycol ............................................................ 3.0 Amerchol L-101 ............................................................. 3.0 Polyoxyethylene propylene glycol monostearate ................................. 2.0 Polyoxyethylene stearate ..................................................... 2.0 Glyceryl monostearate, acid stable ............................................ 17.0 Water ...................................................................... 28.0 Chlorhydrol 50% solution ..................................................... 38.0 Titanium dioxide ............................................................ 1.0 Preservative ................................................................ q. s. Procedure: Add the water to the melted oils with the temperature of both phases at 80øC. Mix slowly until well mixed. Add the Chlorhydrol solution, titanium dioxide and preserva- tive while continuing the mixing. Mix until cool and remix later if necessary. HAiR TREATMENT CREAM This hair treatment formula is valuable for other purposes as well. Al- though very emollient and with many of the characteristics of a water-in- oil cream, the preparation inverts to oil-in-water upon the addition of water, and is then readily washed off leaving an emollient residual film. Formula No. 4 Acetylated lanolin alcohols (liquid fraction) ... or .._ Acetylated lanolin ........................................................... 3.5% Glyceryl monostearate, self emulsifying ......................................... 13.5 Spermaceti .................................................................. 1.5 Amerchol L-101 ............................................................. 9.0 Mineral oil, 70 vis ........................................................... 8.5 Glycerin .................................................................... 4.5 Water ...................................................................... 59.5 Preservative and Perfume ..................................................... q. s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases at 85øC. Mix slowly until cool and remix the following day.