ACETYLATED LANOLIN DERIVATIVES 351 Formula No. 2 Acetylated Lanolin Alcohol (liquid fraction) ..................................... 3.0% Stearic acid ................................................................. 18.0 Cetyl alcohol ................................................................. 5 Amerchol L-101 .............................................................. 5 Sodium hydroxide ............................................................ 8 Propylene glycol .......................................................... 14.0 Water ...................................................................... 63.2 Preservative and Perfume ...................................................... q s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases at 85øC. Mix slowly until cool and remix the following day. ANTIPERSPIRANT CREAM Antiperspirants formulated with acetylated lanolin products impart a non-greasy, highly emollient film which does not interfere with the activity of the aluminum chlorhydroxide complex. This formulation has a glossy surface and a smooth texture and is quite resistant to drying out. Formula No. 3 Acetylated lanolin... or ... Acetylated lanolin alcohols (liquid iYaction) ..................................... :2.0% Spermaceti .................................................................. 4.0 Propylene glycol ............................................................ 3.0 Amerchol L-101 ............................................................. 3.0 Polyoxyethylene propylene glycol monostearate ................................. 2.0 Polyoxyethylene stearate ..................................................... 2.0 Glyceryl monostearate, acid stable ............................................ 17.0 Water ...................................................................... 28.0 Chlorhydrol 50% solution ..................................................... 38.0 Titanium dioxide ............................................................ 1.0 Preservative ................................................................ q. s. Procedure: Add the water to the melted oils with the temperature of both phases at 80øC. Mix slowly until well mixed. Add the Chlorhydrol solution, titanium dioxide and preserva- tive while continuing the mixing. Mix until cool and remix later if necessary. HAiR TREATMENT CREAM This hair treatment formula is valuable for other purposes as well. Al- though very emollient and with many of the characteristics of a water-in- oil cream, the preparation inverts to oil-in-water upon the addition of water, and is then readily washed off leaving an emollient residual film. Formula No. 4 Acetylated lanolin alcohols (liquid fraction) ... or .._ Acetylated lanolin ........................................................... 3.5% Glyceryl monostearate, self emulsifying ......................................... 13.5 Spermaceti .................................................................. 1.5 Amerchol L-101 ............................................................. 9.0 Mineral oil, 70 vis ........................................................... 8.5 Glycerin .................................................................... 4.5 Water ...................................................................... 59.5 Preservative and Perfume ..................................................... q. s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases at 85øC. Mix slowly until cool and remix the following day.

352 JOURNAL OF THE SOCIETY OF COSMETIC CHEMIS•:S ALL-PuRPOSE CREAM Oil-in-Water A soft all-purpose cream of glossy texture--this emollient cream is non- whitening on rubbing out. It may be washed off or left on. In either case an emollient non-greasy film is imparted to the skin. Formula No. 5 Acetylated lanolin alcohols (liquid fraction) ..................................... 10.0% Acetylated lanolin ........................................................... 2.0 Diethylene glycol monostearate C .............................................. 2.0 Stearic acid ................................................................. 2.0 Cetyl alcohol ................................................................. 5 Triethanolamine ............................................................. 1.0 Water ...................................................................... 82.5 Preservative and Perfume ..................................................... q. s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases at 85øC. Mix slowly until cool and remix the following day. COLD CREAM This is a very smooth-textured formulation with a whipped cream con- sistency. It has unusually good spreading and cleansing properties as well as excellent stability. Formula No. 6 Acetylated lanolin... or ... Acetylated lanolin alcohols (liquid fraction) ..................................... 1.0% Beeswax .................................................................... 17.0 Mineral oil, 70 vis ........................................................... 45.0 Amerchol L-101 ............................................................. 3.0 Water ...................................................................... 33.0 Borax ...................................................................... 1.0 Preservative and Perfume ..................................................... q. s. Procedure: Add the water containing the water-soluble materials to the melted oils with the temperature of both phases at 85øC. Mix until cool and fill containers. ANHYDROUS PREPARATIONS Brilliantly clear oil solutions are readily formulated with these acetylated lanolin derivatives. The products are clearly soluble in cold mineral oil resulting in prepara- tions which are emollient and also hydrophobic: an obvious advantage where it is desired to protect against wetting. Both the acetylated lanolin and acetylated lanolin alcohol products have been tested for spectral transmittance in the ultraviolet region of the spec- trum with a quartz prism monochromator. The results indicate that these products are not effective sunscreens. However, the use of these products as inclusions in sunscreen preparations is a valuable application since spread, penetration, emollience and hydrophobic activity are advan- tages to be gained. Further tests must be carried out on humans to com- plete their evaluation in sunscreen formulations.