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]. Cosmet. Sci.) 58, 535-537 (September/October 2007) Abstracts Journal of the Society of Cosmetic Chemists Japan Vol. 41, No. 1, 2007* Development of Nanomaterials by Using Supercritical perfonnance nanomaterials for medicines, cosmetics, Carbon Dioxide -Establishment of New Preparation foods, etc., with an environment-friendly alternative Method ofNiosomes- Kinka Ri NIKKOL GROUP, Cosmos Technical Center Co., Ltd . 3-24-3, Hasune, Itabashi-ku, Tokyo 174-0046, Japan solvent, supercritical CO2. Non-Invasive Methods for Assessment of Dermal UV Damage (II) Ai Oba*, Takumichi Sugiyama** Niosomes (Nonionic surfactant vesicles)just like liposomes Skin Research and Technology Department*, Skin Care have the potential to be used as carriers of active Products R&D Department**, POLA Chemical Industries, ingredients for topical usage, such as cosmetics and Inc., *560, Kashio-cho, Totsuka-ku, Yokohama 244-0812, medicines. The conventional methods for preparing Japan, **27-1, Takashimadai, Kanagawa-ku, Yokohama vesicles have been briefly reviewed. Vesicles are, however, 221-0833, Japan prepared basically by using organic solvents, such as chloroform, ethers, etc., which are harmful to the human One of the important approaches in cosmetics to prevent body. The object of this study was to optimize the process the development of skin aging symptoms such as wrinkles for preparing one kind of nanomaterials, niosomes, by is to treat the skin in the early photoaging stage. However, using a supercritical reverse phase evaporation method it is difficult for most cosmetic users to perceive the degree (scRPE method) without using any co-solvents. Formation of their skin damage caused by chronic UV exposure, of niosomes of nonionic surfactants has been studied based especially in the dermis, Therefore, the establishment of on the solubility behavior of nonionic surfactants in non-invasive methods for the assessment of dennal UV supercritical CO2 (scCO2). The formation ability of damage is to be expected. In this study, we measured the niosomes was evaluated by trapping efficiency measured facial skin of 127 healthy Japanese women (aged 25-38) by the glucose dialysis technique. Furthermore, the using the Cutometer, and Resiliometer which we invented. structure of niosomes was of a large unilamellar vesicle as Mechanical parameters obtained by the Cutometer, Ur and revealed by freeze-fracture transmission electron Ur/Uf, which are correlated with the accumulation of microscopy (FF-TEM) images and DSC measurement. This denatured elastic fibers in our previous study, linearly new method is considered to be able to encapsulate decreased with age, and correlated with water content of different useful active ingredients easily and gain high the stratum corneum. On the other hand, a Resiliometer * These abstracts appear as they were originally published. They have not been edited by the Journal of Cosmetic Science. 535