]. Cosmet. Sci.) 58, 535-537 (September/October 2007) Abstracts Journal of the Society of Cosmetic Chemists Japan Vol. 41, No. 1, 2007* Development of Nanomaterials by Using Supercritical perfonnance nanomaterials for medicines, cosmetics, Carbon Dioxide -Establishment of New Preparation foods, etc., with an environment-friendly alternative Method ofNiosomes- Kinka Ri NIKKOL GROUP, Cosmos Technical Center Co., Ltd . 3-24-3, Hasune, Itabashi-ku, Tokyo 174-0046, Japan solvent, supercritical CO2. Non-Invasive Methods for Assessment of Dermal UV Damage (II) Ai Oba*, Takumichi Sugiyama** Niosomes (Nonionic surfactant vesicles)just like liposomes Skin Research and Technology Department*, Skin Care have the potential to be used as carriers of active Products R&D Department**, POLA Chemical Industries, ingredients for topical usage, such as cosmetics and Inc., *560, Kashio-cho, Totsuka-ku, Yokohama 244-0812, medicines. The conventional methods for preparing Japan, **27-1, Takashimadai, Kanagawa-ku, Yokohama vesicles have been briefly reviewed. Vesicles are, however, 221-0833, Japan prepared basically by using organic solvents, such as chloroform, ethers, etc., which are harmful to the human One of the important approaches in cosmetics to prevent body. The object of this study was to optimize the process the development of skin aging symptoms such as wrinkles for preparing one kind of nanomaterials, niosomes, by is to treat the skin in the early photoaging stage. However, using a supercritical reverse phase evaporation method it is difficult for most cosmetic users to perceive the degree (scRPE method) without using any co-solvents. Formation of their skin damage caused by chronic UV exposure, of niosomes of nonionic surfactants has been studied based especially in the dermis, Therefore, the establishment of on the solubility behavior of nonionic surfactants in non-invasive methods for the assessment of dennal UV supercritical CO2 (scCO2). The formation ability of damage is to be expected. In this study, we measured the niosomes was evaluated by trapping efficiency measured facial skin of 127 healthy Japanese women (aged 25-38) by the glucose dialysis technique. Furthermore, the using the Cutometer, and Resiliometer which we invented. structure of niosomes was of a large unilamellar vesicle as Mechanical parameters obtained by the Cutometer, Ur and revealed by freeze-fracture transmission electron Ur/Uf, which are correlated with the accumulation of microscopy (FF-TEM) images and DSC measurement. This denatured elastic fibers in our previous study, linearly new method is considered to be able to encapsulate decreased with age, and correlated with water content of different useful active ingredients easily and gain high the stratum corneum. On the other hand, a Resiliometer * These abstracts appear as they were originally published. They have not been edited by the Journal of Cosmetic Science. 535

536 JOURNAL OF COSMETIC SCIENCE parameter, tau, which correlates with the three-dimensional combination of NIR-DR spectroscopy and principal structures of dermal collagen fibers, did not change component analysis (PCA) were applied to development of linearly, but showed interesting behavior with age. In an evaluation of hair damage and we found the most addition, no correlation was shown between tau and water suitable wavenumber region (5060-4500 cm-I) for the content of the stratum comeum. These results suggested gradual changes of the matrix components in the dermis with age. However, most of the subjects without obvious skin aging symptoms did not notice such changes in the dermis. We think that the estimation of the degree of UV­ induced skin damage in the early photoaging stage using a variety of non-invasive methods is beneficial for cosmetic evaluation of hair damage. In this study, we developed a new evaluation method that can indicate hair interior and surface damage conditions induced by chemical treatments in a simple, rapid, non-destructive manner based on NIR­ DR spectroscopy by putting a fiber probe on hair. users to notice their skin condition and to find an Continuous Three-Dimensional Examination of Interior appropriate skin care solution. Hair Structure Ken-ichi Tanaka, Yutaka Tango, Koichi Shimmoto A Non-Destructive Method for Assessing Interior and Research & Development Headquarter, KOSE Corporation Surface Hair Damage by Near Infrared Spectroscopy 48-18, Sakae-cho, Kita-ku, Tokyo 114-0005, Japan Yuta Miyamae*, Yumika Yamakawa*, Yukihiro Ozaki** The ability to examine interior hair structure is very POLA Chemical Industries, Inc.*, Department of important in designing effective hair products. But a non­ Chemistry, School of Science and Technology, Kwansei- destructive method for continuous, full-color examination Gakuin University**, *560, Kashio-cho, Totsuka-ku, of the interior hair structure has been lacking. This study Yokohama 244-0812, Japan, **2-1, Gakuen, Sanda 669- proposes a new method that enables non-destructive and 1337,Japan continuous measurement of the interior hair structure with color information. In our method, Optical CT (OCT) is This paper reports a non-destructive method for evaluating used for reconstruction of interior hair structure. Our new hair interior and surface damage based on near-infrared theories enabled us to solve the crucial problem of an OCT (NIR) diffuse reflectance (DR) spectroscopy. It is important system related to a large observational error caused by to know the extent of chemical damage in the interior and internal light scattering, and to make practical application surface proteins of the hair in order to choose an possible. A new OCT system based on our method was appropriate restoration agent or chemical treatment. implemented. This system displayed sufficient accuracy Unfortunately, though there are many simple and non- when the phantom image was measured, and by observing destructive methods for evaluating the hair surface, the human hair, clear and full-color cross-sectional images existing evaluation methods for monitoring chemical were obtained without destruction of the sample. When the changes in the interior proteins are very complicated and bleaching and dyeing processes were continuously destructive. Therefore, we have attempted to develop a new measured, changes in the interior hair with time could be non-destructive method to evaluate the damage to the hair observed. These results clearly indicate that our new interior and surface simultaneously by using NIR-DR method provides a powerful tool in research and product spectroscopy. The key to this study was that the development. Vol. 41, No. 2, 2007 An Introduction of Filling up and Molding Technology In the production plant, efficiency improvement and high such as Powder Foundation and of Some Cases in the quality are called for. In addition, a lot of problems that Factory cannot be predicted in the laboratory occur. This lecture Tatsuya Hasegawa introduces the problems and solutions to the powder Manufacturing Technology R&D Laboratories, POLA Chemical Industries, Inc. 1234, Aino, Hukuroi 437_8765, molding that occur on the production site from the Japan viewpoint of a production system engineer.