657 Bidirectional Gut-Skin Axis
(125) Brenner M, Hearing VJ. The protective role of melanin against UV damage in human skin. Photochem
Photobiol. 2008 84(3):539–549. doi:10.1111/j.1751-1097.2007.00226.x
(126) Huang H–C, Chang T-M. Antioxidative properties and inhibitory effect of Bifidobacterium adolescentis
on melanogenesis. World J Microbiol Biotechnol. 2012 28(9):2903–2912. doi:10.1007/s11274-012-1096-0
(127) Lim HY, Jeong D, Park SH, et al. Antiwrinkle and antimelanogenesis effects of Tyndallized Lactobacillus
acidophilus KCCM12625P. Int J Mol Sci. February 2020 21(5). doi:10.3390/ijms21051620
(128) Liu W-S, Kuan Y-D, Chiu K-H, et al. The extract of Rhodobacter sphaeroides inhibits melanogenesis
through the MEK/ERK signaling pathway. Mar Drugs. 2013 11(6):1899–1908. doi:10.3390/
md11061899
(129) Sinha S, Lin G, Ferenczi K. The skin microbiome and the gut-skin axis. Clin Dermatol. 2021 39(5):829–839.
doi:10.1016/j.clindermatol.2021.08.021
(130) Guéniche A, David P, Philippe B, Stephanie S, Elif B, Isabelle C-H. Probiotics for photoprotection. Derm
Endocrinol. 2009 1:275–279.
(131) Zhou X, Du H-H, Ni L, et al. Nicotinamide mononucleotide combined with Lactobacillus fermentum
TKSN041 reduces the photoaging damage in murine skin by activating AMPK signaling pathway.
Front Pharmacol. March 2021 12:643089. doi:10.3389/fphar.2021.643089
(132) Lee K, Kim HJ, Kim SA, Park S-D, Shim J-J, Lee J-L. Exopolysaccharide from Lactobacillus plantarum
HY7714 protects against skin aging through skin-gut axis communication. Molecules. March 2021 26(6).
doi:10.3390/molecules26061651
(133) Baba H, Masuyama A, Yoshimura C, Aoyama Y, Takano T, Ohki K. Oral intake of Lactobacillus
helveticus-fermented milk whey decreased transepidermal water loss and prevented the onset of sodium
dodecyl sulfate-induced dermatitis in mice. Biosci Biotechnol Biochem. 2010 74(1):18–23. doi:10.1271/
bbb.90370
(134) You G-E, Jung B-J, Kim H-R, Kim H-G, Kim T-R, Chung D-K. Lactobacillus sakei lipoteichoic
acid inhibits MMP-1 induced by UVA in normal dermal fibroblasts of human. J Microbiol Biotechnol.
2013 23(10):1357–1364. doi:10.4014/jmb.1306.06026
(135) Pandey KR, Naik SR, Vakil BV. Probiotics, prebiotics and Synbiotics—A review. J Food Sci Technol.
2015 52(12):7577–7587. doi:10.1007/s13197-015-1921-1
(136) Scholz-Ahrens KE, Adolphi B, Rochat F, et al. Effects of probiotics, prebiotics, and Synbiotics on mineral
metabolism in ovariectomized rats—impact of bacterial mass, intestinal absorptive area and reduction
of bone turn-over. NFS J. 2016 3:41–50. doi:10.1016/j.nfs.2016.03.001
(137) Watanabe J, Sasajima N, Aramaki A, Sonoyama K. Consumption of fructo-oligosaccharide reduces
2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. Br J Nutr. 2008 100(2):339–346.
doi:10.1017/S0007114507901221
(138) Lolou V, Panayiotidis MI. Functional role of probiotics and prebiotics on skin health and disease.
Fermentation. May 2019 5(2). doi:10.3390/fermentation5020041
(139) Kimoto-Nira H, Aoki R, Sasaki K, Suzuki C, Mizumachi K. Oral intake of heat-killed cells of Lactococcus
lactis strain H61 promotes skin health in women. J Nutr Sci. December 2012 1:e18. doi:10.1017/jns.2012.22
(140) Majeed M, Nagabhushanam K, Paulose S, Rajalakshmi HR, Mundkur L. A randomized double-
blind, placebo-controlled study to evaluate the anti-skin-aging effect of LactoSporin—the extracellular
metabolite from Bacillus coagulans (Weizmannia coagulans) MTCC 5856 in.healthy female volunteers.
Clin Cosmet Investig Dermatol. 2023 16:769–782. doi:10.2147/CCID.S403418
(141) Aguirre-Cruz G, León-López A, Cruz-Gómez V, Jiménez-Alvarado R, Aguirre-Álvarez G. Collagen
hydrolysates for skin protection: oral administration and topical formulation. Antioxidants (Basel).
February 2020 9(2). doi:10.3390/antiox9020181
(142) Sugihara F, Inoue N. Clinical effects of collagen hydrolysates ingestion on UV-induced pigmented spots
of human skin: A preliminary study. Health Sci. 2012 28:15–23.
(143) Schwartz SR, Park J. Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract
enhanced blood microcirculation and reduced facial aging signs. Clin Interv Aging. 2012 7:267–273.
doi:10.2147/CIA.S32836
(125) Brenner M, Hearing VJ. The protective role of melanin against UV damage in human skin. Photochem
Photobiol. 2008 84(3):539–549. doi:10.1111/j.1751-1097.2007.00226.x
(126) Huang H–C, Chang T-M. Antioxidative properties and inhibitory effect of Bifidobacterium adolescentis
on melanogenesis. World J Microbiol Biotechnol. 2012 28(9):2903–2912. doi:10.1007/s11274-012-1096-0
(127) Lim HY, Jeong D, Park SH, et al. Antiwrinkle and antimelanogenesis effects of Tyndallized Lactobacillus
acidophilus KCCM12625P. Int J Mol Sci. February 2020 21(5). doi:10.3390/ijms21051620
(128) Liu W-S, Kuan Y-D, Chiu K-H, et al. The extract of Rhodobacter sphaeroides inhibits melanogenesis
through the MEK/ERK signaling pathway. Mar Drugs. 2013 11(6):1899–1908. doi:10.3390/
md11061899
(129) Sinha S, Lin G, Ferenczi K. The skin microbiome and the gut-skin axis. Clin Dermatol. 2021 39(5):829–839.
doi:10.1016/j.clindermatol.2021.08.021
(130) Guéniche A, David P, Philippe B, Stephanie S, Elif B, Isabelle C-H. Probiotics for photoprotection. Derm
Endocrinol. 2009 1:275–279.
(131) Zhou X, Du H-H, Ni L, et al. Nicotinamide mononucleotide combined with Lactobacillus fermentum
TKSN041 reduces the photoaging damage in murine skin by activating AMPK signaling pathway.
Front Pharmacol. March 2021 12:643089. doi:10.3389/fphar.2021.643089
(132) Lee K, Kim HJ, Kim SA, Park S-D, Shim J-J, Lee J-L. Exopolysaccharide from Lactobacillus plantarum
HY7714 protects against skin aging through skin-gut axis communication. Molecules. March 2021 26(6).
doi:10.3390/molecules26061651
(133) Baba H, Masuyama A, Yoshimura C, Aoyama Y, Takano T, Ohki K. Oral intake of Lactobacillus
helveticus-fermented milk whey decreased transepidermal water loss and prevented the onset of sodium
dodecyl sulfate-induced dermatitis in mice. Biosci Biotechnol Biochem. 2010 74(1):18–23. doi:10.1271/
bbb.90370
(134) You G-E, Jung B-J, Kim H-R, Kim H-G, Kim T-R, Chung D-K. Lactobacillus sakei lipoteichoic
acid inhibits MMP-1 induced by UVA in normal dermal fibroblasts of human. J Microbiol Biotechnol.
2013 23(10):1357–1364. doi:10.4014/jmb.1306.06026
(135) Pandey KR, Naik SR, Vakil BV. Probiotics, prebiotics and Synbiotics—A review. J Food Sci Technol.
2015 52(12):7577–7587. doi:10.1007/s13197-015-1921-1
(136) Scholz-Ahrens KE, Adolphi B, Rochat F, et al. Effects of probiotics, prebiotics, and Synbiotics on mineral
metabolism in ovariectomized rats—impact of bacterial mass, intestinal absorptive area and reduction
of bone turn-over. NFS J. 2016 3:41–50. doi:10.1016/j.nfs.2016.03.001
(137) Watanabe J, Sasajima N, Aramaki A, Sonoyama K. Consumption of fructo-oligosaccharide reduces
2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. Br J Nutr. 2008 100(2):339–346.
doi:10.1017/S0007114507901221
(138) Lolou V, Panayiotidis MI. Functional role of probiotics and prebiotics on skin health and disease.
Fermentation. May 2019 5(2). doi:10.3390/fermentation5020041
(139) Kimoto-Nira H, Aoki R, Sasaki K, Suzuki C, Mizumachi K. Oral intake of heat-killed cells of Lactococcus
lactis strain H61 promotes skin health in women. J Nutr Sci. December 2012 1:e18. doi:10.1017/jns.2012.22
(140) Majeed M, Nagabhushanam K, Paulose S, Rajalakshmi HR, Mundkur L. A randomized double-
blind, placebo-controlled study to evaluate the anti-skin-aging effect of LactoSporin—the extracellular
metabolite from Bacillus coagulans (Weizmannia coagulans) MTCC 5856 in.healthy female volunteers.
Clin Cosmet Investig Dermatol. 2023 16:769–782. doi:10.2147/CCID.S403418
(141) Aguirre-Cruz G, León-López A, Cruz-Gómez V, Jiménez-Alvarado R, Aguirre-Álvarez G. Collagen
hydrolysates for skin protection: oral administration and topical formulation. Antioxidants (Basel).
February 2020 9(2). doi:10.3390/antiox9020181
(142) Sugihara F, Inoue N. Clinical effects of collagen hydrolysates ingestion on UV-induced pigmented spots
of human skin: A preliminary study. Health Sci. 2012 28:15–23.
(143) Schwartz SR, Park J. Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract
enhanced blood microcirculation and reduced facial aging signs. Clin Interv Aging. 2012 7:267–273.
doi:10.2147/CIA.S32836