ftl --;- e.-= )C - G) "C ,n -= 1 C E .2 g 'S E a, m m :::s C 0" ftl u, .c G) C,) Improvement Q a Improvement b 10 0 -5 -10 -15 MOISTURIZER EFFICACY 437 Ability of Lotions to Reduce Skin Flaking as Determined as Desquamation Index in a Mini Regression Test Baselin Day7 Evaluation -+-Lotion H -Lotion GR • Lotion B - -- Lotion W --:. - No Product Ability of Lotions to Increase Skin Hydration as Determined by Conductance in a Mini Regression Test 120 �--- - ------- - -----� Baseline Day4 Day7 -20 �---------------------' Evaluation -+-Lotion H ---Lotion GR - - -• -Lotion B ---Lotion W - -:11- - No Product Figure 1. Alleviation of skin dryness. The ability of lotions to moisturize the skin as measured by a mini-regression test. The skin parameters assessed were: (a) Desquamation index as a measure of skin scaling. (6) Conductance as a measure of skin hydration. (c) Squamometry as a measure of surface corneocyte integrity. (d) Dryness assessed by a trained observer. (Figure continued on following page.) Figure ld shows the dryness scores as assessed by a trained observer. Here treatment with lotion GR significantly reduced observable scaling (when compared to the "no product" site) on Day 4. This benefit was maintained on Day 7 after treatment ceased. BENEFIT: PREVENTION OF DRYNESS-HAND-WASH TEST At all time measurements, product GR showed a significantly greater ability to hydrate

438 Improvement C Improvement d CD 20 :'._ 15 e 10 e (.) 5 0 JOURNAL OF COSMETIC SCIENCE Ability of Lotions to Remove Damaged Surface Corneocytes as Determined by Squamometry in a Mini Regression Test Lotion H Lotion GR Lotion B Lotion W No Product Ability of Lotions to Reduce Observable Dryness as Determined in a Mini-Regression Test 0 .---------------.----------.---------, Day4 Day? en_ :E ! -0.2 � UJ : i _a -0.4 '- E 0 0 �.t: 1. CD -0.6 � g, CD CG .! c3 -0.8 o- -1 �-------------------' Evaluation Figure 1. (continued) ---+-Lotion H -Lotion GR ·*··Lotion B -LotionW -·• · No Product the skin than the other study products (W and H) and the "no product" control, using conductance as a measure (p 0.01) (Figure 2a). Application of product W had a benefit, as conductance was higher than with the "no product" control. On Day 3, D-Squames® patches were collected from all test areas. They were subse­ quently stained and measured, using colorimeter C* values. Product GR was effective at removing damaged surface corneocytes, having a significantly lower C* value than the "no product" control and product H (Figure 26). For observer-scored scaling, a within-subject ANOVA showed that all the products were effective, with a significant reduction in scaling compared with the "no product" control