631 The Skin Microbiome and Aging
(6) Kim HJ, Oh HN, Park T, et al. Aged related human skin microbiome and mycobiome in Korean
women. Scientific Reports. 2022 12(1). doi:10.1038/s41598-022-06189-5
(7) Howard B, Bascom CC, Hu P, et al. Aging-associated changes in the adult human skin microbiome and
the host factors that affect skin microbiome composition. Journal of Investigative Dermatology. 2021 142(7).
doi:10.1016/j.jid.2021.11.029
(8) Myers T, Bouslimani A, Huang S, et al. A multi-study analysis enables identification of potential
microbial features associated with skin aging signs. Frontiers in aging. 2024 4(11). doi:10.3389/fragi
.2023.1304705
(9) Kim JH, Son SM, Park H, et al. Taxonomic profiling of skin microbiome and correlation with
clinical skin parameters in healthy Koreans. Scientific Reports. 2021 11(1):16269. doi:10.1038/s41598
-021-95734-9
(10) Dimitriu PA, Iker B, Malik K, Leung H, Mohn WW, Hillebrand GG. New insights into the intrinsic
and extrinsic factors that shape the human skin microbiome. Guttman DS, ed. mBio. 2019 10(4).
doi:10.1128/mbio.00839-19
(11) Li Z, Bai X, Peng T, et al. New insights into the skin microbial communities and skin aging. Frontiers
in Microbiology. 2020 11(11). doi:10.3389/fmicb.2020.565549
(12) Cappellato M, Baruzzo G, Patuzzi I, Di Camillo B. Modeling microbial community networks: methods
and tools. Current Genomics. 2020 21(22). doi:10.2174/1389202921999200905133146
(13) Chen Y, Knight R, Gallo RL. Evolving approaches to profiling the microbiome in skin disease. Front
Immunol. 2023 14(14). doi:10.3389/fimmu.2023.1151527
(14) Larson PJ, Zhou W, Santiago A, et al. Associations of the skin, oral and gut microbiome with aging,
frailty and infection risk reservoirs in older adults. Nature Aging. 2022 2(10):941–955. doi:10.1038/
s43587-022-00287-9
(15) Xia J, Li Z, Zhong Q, et al. Integration of skin phenome and microbiome reveals the key role of bacteria
in human skin aging. Europe PMC. doi:10.21203/rs.3.rs-2629420/v1
(16) Zhou W, Fleming E, Legendre G, et al. Skin microbiome attributes associate with biophysical skin
ageing. Experimental Dermatology. 2023 32(9). doi:10.1111/exd.14863
(17) Garlet A, Andre-Frei V, Del Bene N, et al. Facial skin microbiome composition and functional shift with
aging. Microorganisms. 2024 12(5):1021. doi:10.3390/microorganisms12051021
(18) Dreno B, Martin R, Moyal D, Henley JB, Khammari A, Seité S. Skin microbiome and acne vulgari:
Staphylococcus, a new actor in acne. Experimental Dermatology. 2017 26(9):798–803. doi:10.1111/exd
.13296
(19) Lee YB, Byun EJ, Kim HS. Potential role of the microbiome in acne: a comprehensive review. Journal of
Clinical Medicine. 2019 8(7):987. doi:10.3390/jcm8070987
(20) Grice EA, Segre JA. The skin microbiome. Nature Reviews Microbiology. 2011 9(4):244–253. doi:10.1038/
nrmicro2537
(21) Shine EE, Crawford JM. Molecules from the microbiome. Annual Review of Biochemistry. 2021 90(1):789–
815. doi:10.1146/annurev-biochem-080320-115307
(22) Farage MA, Miller KW, Elsner P, Maibach HI. Intrinsic and extrinsic factors in skin ageing: a review.
International Journal of Cosmetic Science. 2008 30(2):87–95. doi:10.1111/j.1468-2494.2007.00415.x
(23) Langton AK, Sherratt MJ, Griffiths CEM, Watson REB. Review article: a new wrinkle on old skin:
the role of elastic fibres in skin ageing. International Journal of Cosmetic Science. 2010 32(5):330–339.
doi:10.1111/j.1468-2494.2010.00574.x
(24) Park H, Arellano K, Lee Y, et al. Pilot study on the forehead skin microbiome and short chain fatty acids
depending on the SC functional index in Korean cohorts. Microorganisms. 2021 9(11):2216. doi:10.3390/
microorganisms9112216
(25) Bielfeldt S, Springmann G, Seise M, Wilhelm KP, Callaghan T. An updated review of clinical methods
in the assessment of ageing skin -new perspectives and evaluation for claims support. International
Journal of Cosmetic Science. 2018 40(4):348–355. doi:10.1111/ics.12484
(6) Kim HJ, Oh HN, Park T, et al. Aged related human skin microbiome and mycobiome in Korean
women. Scientific Reports. 2022 12(1). doi:10.1038/s41598-022-06189-5
(7) Howard B, Bascom CC, Hu P, et al. Aging-associated changes in the adult human skin microbiome and
the host factors that affect skin microbiome composition. Journal of Investigative Dermatology. 2021 142(7).
doi:10.1016/j.jid.2021.11.029
(8) Myers T, Bouslimani A, Huang S, et al. A multi-study analysis enables identification of potential
microbial features associated with skin aging signs. Frontiers in aging. 2024 4(11). doi:10.3389/fragi
.2023.1304705
(9) Kim JH, Son SM, Park H, et al. Taxonomic profiling of skin microbiome and correlation with
clinical skin parameters in healthy Koreans. Scientific Reports. 2021 11(1):16269. doi:10.1038/s41598
-021-95734-9
(10) Dimitriu PA, Iker B, Malik K, Leung H, Mohn WW, Hillebrand GG. New insights into the intrinsic
and extrinsic factors that shape the human skin microbiome. Guttman DS, ed. mBio. 2019 10(4).
doi:10.1128/mbio.00839-19
(11) Li Z, Bai X, Peng T, et al. New insights into the skin microbial communities and skin aging. Frontiers
in Microbiology. 2020 11(11). doi:10.3389/fmicb.2020.565549
(12) Cappellato M, Baruzzo G, Patuzzi I, Di Camillo B. Modeling microbial community networks: methods
and tools. Current Genomics. 2020 21(22). doi:10.2174/1389202921999200905133146
(13) Chen Y, Knight R, Gallo RL. Evolving approaches to profiling the microbiome in skin disease. Front
Immunol. 2023 14(14). doi:10.3389/fimmu.2023.1151527
(14) Larson PJ, Zhou W, Santiago A, et al. Associations of the skin, oral and gut microbiome with aging,
frailty and infection risk reservoirs in older adults. Nature Aging. 2022 2(10):941–955. doi:10.1038/
s43587-022-00287-9
(15) Xia J, Li Z, Zhong Q, et al. Integration of skin phenome and microbiome reveals the key role of bacteria
in human skin aging. Europe PMC. doi:10.21203/rs.3.rs-2629420/v1
(16) Zhou W, Fleming E, Legendre G, et al. Skin microbiome attributes associate with biophysical skin
ageing. Experimental Dermatology. 2023 32(9). doi:10.1111/exd.14863
(17) Garlet A, Andre-Frei V, Del Bene N, et al. Facial skin microbiome composition and functional shift with
aging. Microorganisms. 2024 12(5):1021. doi:10.3390/microorganisms12051021
(18) Dreno B, Martin R, Moyal D, Henley JB, Khammari A, Seité S. Skin microbiome and acne vulgari:
Staphylococcus, a new actor in acne. Experimental Dermatology. 2017 26(9):798–803. doi:10.1111/exd
.13296
(19) Lee YB, Byun EJ, Kim HS. Potential role of the microbiome in acne: a comprehensive review. Journal of
Clinical Medicine. 2019 8(7):987. doi:10.3390/jcm8070987
(20) Grice EA, Segre JA. The skin microbiome. Nature Reviews Microbiology. 2011 9(4):244–253. doi:10.1038/
nrmicro2537
(21) Shine EE, Crawford JM. Molecules from the microbiome. Annual Review of Biochemistry. 2021 90(1):789–
815. doi:10.1146/annurev-biochem-080320-115307
(22) Farage MA, Miller KW, Elsner P, Maibach HI. Intrinsic and extrinsic factors in skin ageing: a review.
International Journal of Cosmetic Science. 2008 30(2):87–95. doi:10.1111/j.1468-2494.2007.00415.x
(23) Langton AK, Sherratt MJ, Griffiths CEM, Watson REB. Review article: a new wrinkle on old skin:
the role of elastic fibres in skin ageing. International Journal of Cosmetic Science. 2010 32(5):330–339.
doi:10.1111/j.1468-2494.2010.00574.x
(24) Park H, Arellano K, Lee Y, et al. Pilot study on the forehead skin microbiome and short chain fatty acids
depending on the SC functional index in Korean cohorts. Microorganisms. 2021 9(11):2216. doi:10.3390/
microorganisms9112216
(25) Bielfeldt S, Springmann G, Seise M, Wilhelm KP, Callaghan T. An updated review of clinical methods
in the assessment of ageing skin -new perspectives and evaluation for claims support. International
Journal of Cosmetic Science. 2018 40(4):348–355. doi:10.1111/ics.12484
