438 Improvement C Improvement d CD 20 :'._ 15 e 10 e (.) 5 0 JOURNAL OF COSMETIC SCIENCE Ability of Lotions to Remove Damaged Surface Corneocytes as Determined by Squamometry in a Mini Regression Test Lotion H Lotion GR Lotion B Lotion W No Product Ability of Lotions to Reduce Observable Dryness as Determined in a Mini-Regression Test 0 .---------------.----------.---------, Day4 Day? en_ :E ! -0.2 � UJ : i _a -0.4 '- E 0 0 �.t: 1. CD -0.6 � g, CD CG .! c3 -0.8 o- -1 �-------------------' Evaluation Figure 1. (continued) ---+-Lotion H -Lotion GR ·*··Lotion B -LotionW -·• · No Product the skin than the other study products (W and H) and the "no product" control, using conductance as a measure (p 0.01) (Figure 2a). Application of product W had a benefit, as conductance was higher than with the "no product" control. On Day 3, D-Squames® patches were collected from all test areas. They were subse­ quently stained and measured, using colorimeter C* values. Product GR was effective at removing damaged surface corneocytes, having a significantly lower C* value than the "no product" control and product H (Figure 26). For observer-scored scaling, a within-subject ANOVA showed that all the products were effective, with a significant reduction in scaling compared with the "no product" control

Improvement a 50 45 40 35 Improvement 30 b s en u u,-CD ,:, - ca I. u 0 ti) U-.:t U) 0 I. - CD Improvement ti) C ABILITY OF LOTIONS TO HYDRATE THE SKIN IN A HAND WASH STUDY 120 �------------------ - - 80 -+-LotionH -Lotion GR Lotion W Baseline .. · · .. i;ay O pm · · * · · No Product -40 ··· �············· ·············x.. �o..L_ ____________________x·· ..._J Evaluation The Ability of Lotions to Remove Damaged Surface Corneocytes in a Hand Wash Study Lotion H Lotion GR Lotion W No Product Ability of Lotions to Reduce Dry Skin (Scaling) in a Hand Wash Study 3.5 3 .x·············� .. .. 2.5 . •· �·�·--�·�·_ _____ --Lotion H 2 -Lotion GR 1.5 - - -4 - -.i.- Lotion W :--- .. : 1 · · * · · No Product 0.5 0 Baseline DayO pm Day 1 pm Day2 pm Day3 pm Evaluation Figure 2. Prevention of skin dryness. The ability of lotions to prevent soap-inducing dryness on the backs of the hands. The skin parameters assessed were: (a) Conductance as a measure of skin hydration. (b) Squamometry as a measure of surface corneocyte integrity. (c) Dryness assessed by a trained observer.